heinz body การใช้

• Hemichrome formation, followed by a band 3 clustering and the formation of Heinz bodies, can take place during the physiological clearance of damaged red blood cells.
• When a macrophage in the spleen identifies a RBC with a Heinz body, it removes the precipitate and a small piece of the membrane, leading to characteristic " bite cells ".
• Cats may be the predominant species to develop VAS because they have an increased susceptibility to oxidative injury, as evidenced also by an increased risk of Heinz body anemia and acetaminophen toxicity.
• However, if a large number of Heinz bodies are produced, as in the case of G6PD deficiency, some Heinz bodies will nonetheless be visible when viewing RBCs that have been stained with crystal violet.
• However, if a large number of Heinz bodies are produced, as in the case of G6PD deficiency, some Heinz bodies will nonetheless be visible when viewing RBCs that have been stained with crystal violet.
• Unlike an overdose in humans, it is rarely liver damage that is the cause of death, instead methaemoglobin formation and the production of Heinz bodies in red blood cells inhibit oxygen transport by the blood, causing asphyxiation.
• Unlike an overdose in humans, liver damage is rarely the cause of death; instead, methemoglobin formation and the production of Heinz bodies in red blood cells inhibit oxygen transport by the blood, causing asphyxiation ( methemoglobemia and hemolytic anemia ).
• The difference between a normal red blood cell ( RBC ) and a red blood cell with unstable haemoglobin ( such as in the case of haemolytic anaemia ) is that, in a normal RBC, the formation of Heinz bodies is significantly delayed.
• According to the FDA " It was known for some time that propylene glycol caused Heinz Body formation in the red blood cells of cats ( small clumps of proteins seen in the cells when viewed under the microscope ), but it could not be shown to cause overt anemia or other clinical effects.